Antioxidant therapy in male infertility: fact or fiction?

Antioxidant therapy in male infertility: fact or fiction?

Infertile men have higher levels of semen reactive oxygen species (ROS) than do fertile men. High levels of semen ROS can cause sperm dysfunction, sperm DNA damage and reduced male reproductive potential. This observation has led clinicians to treat infertile men with antioxidant supplements. The purpose of this article is to discuss the rationale for antioxidant therapy in infertile men and to...

Laser Therapy for Onychomycosis: Fact or Fiction?

Onychomycosis is a common fungal infection, afflicting some 10% of the adult population in industrialized countries. Aside from cosmetic concerns, onychomycosis can be the cause of toe and foot pain, as well as the underlying etiology for serious secondary bacterial infections and traumatic ulcerations. In select populations, such as diabetics, the latter conditions may even result in loss of a...

Sonofusion – Fact or Fiction?

Sonoluminescence and Sonofusion phenomena may occur when vapor bubbles implode. This paper reviews the status of our understanding of the bubble dynamics involved in these interesting phenomena. In particular, the experimental and analytical evidence supporting the observed production of neutrons and tritium due to thermonuclear fusion within imploding bubble clusters is reviewed. Moreover, pot...

NFRs : Fact or Fiction ?

Fact or fiction

Many previous studies have aimed at spermatogenesis of male murine germ cells in vitro, but no efficient system has been established yet that covers the entire process of mammalian spermatogenesis in a culture dish permanently. In this review, we report on the requirements of spermatogenesis and the current state of different culture methods using testicular tissue fragments, single cell suspen...